Medications Commonly Used in Treating Mast Cell-Related Disorders

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The purpose of this page is to help you untangle the welter of medication brands, names and ingredients, both inside and outside the US. In addition to basic information about the many meds we use, we've provided links to the web sites of major medications.

While we cannot cover every drug that any one of us may take, we've tried to provide information about the medications (mast cell stabilizers, antihistamines, leukotriene blockers, etc.) that tend to be taken or prescribed for mast cell-related disorders.

Legend

      Corticosteroid
    
Epinephrine
    
H1-blocking antihistamine
    H2-blocking antihistamine
    Leukotriene-inhibitor
      Mast cell stabilizers
      NSAIDs
  Discontinued due to safety issues
A

Accolate® 
Brand name for zafirlukast, available by prescription and manufactured in the US by AstraZeneca. Available in the United Kingdom from Roche.

ACT-3 
Brand name for ibuprofen. Available in Australia only.

Adapin 
Brand name for doxepin HCl, available in the US.

Adrenalin 
Brand name for epinephrine inhaler, available OTC in the US.

Adrenalin Chloride 
Brand name for epinephrine injection, available in the US.

Aerius® 
Brand name for desloratadine, available by prescription in Canada only.

Alavert™ 
Brand name for loratadine, manufactured in the US by Wyeth. This OTC tablet is made to "melt in mouth" rather than being swallowed with water.

Aldecin Inhaler 
Brand name for beclomethasone dipropionate. Available in Australia only.

Aleve 
Brand name for naproxen sodium, available OTC in the US.

Allegra® 
Brand name for fexofenadine HCl, available by prescription and manufactured in the US by Aventis Pharmaceuticals Inc. Also available in Canada.

Allegra-D®
Brand name for extended-release tablets that contain 60 mg of fexofenadine HCL (an H1-blocking antihistamine) for immediate-release and 120 mg of pseudoephedrine HCl for extended-release. See Allegra®.

Alleract 
Brand name for triprolidine HCl, available OTC in the US.

Aller-Chlor® 
Brand name for chlorpheniramine maleate, available OTC in the US.

Allerdryl 
Brand name for diphenhydramine HCl, available OTC in Canada.

Allergex 
Brand name for chlorpheniramine maleate, available only in Australia.

Allergy Relief 
Brand name for chlorpheniramine maleate, available OTC in the US.

Allergy Relief Medicine (A.R.M.)
Brand name for tablets containing chlorpheniramine maleate and pseudoephedrine HCl, available OTC in the US.

Allerhist-1 
Brand name for clemastine fumarate, available OTC in the US.

AllerMax Caplets 
Brand name for diphenhydramine HCl, available OTC and manufactured in the US by Pfeiffer Pharmaceuticals, Inc.

Aller-med 
Brand name for diphenhydramine HCl, available OTC in the US.

Allernix 
Brand name for diphenhydramine HCl, available in Canada.

Alocril 
Brand name for nedocromil, used as prescription eye drops to treat allergic reactions in eyes.

Amersol 
Brand name for ibuprofen. Available in Canada only.

Amilon®
Brand name for a product that combines chlorpheniramine maleate, phenindamine, and phenylpropanolamine.

Anaprox 
Brand name for naproxen sodium, available in the US. Also available as Anaprox DS.

Andrumin 
Brand name for dimenhydrinate, available in Australia only.

Anergan 
Brand name for promethazine HCl, available by prescription in the US. Available as Anergan 25 and Anergan 50.

Antihistamine
See Antihistamine.

ANX® 
Brand name for hydroxyzine HCl, available by prescription in the US.

Anxanil® 
Brand name for hydroxyzine HCl, available by prescription in the US.

Apo®-Dimenhydrinate 
Brand name for dimenhydrinate, available in Canada only.

Apo®-Hydroxyzine 
Brand name for hydroxyzine HCl, available in Canada only.

Apo®-Ibuprofen 
Brand name for ibuprofen. Available in Canada only.

Apo®-Napro-Na 
Brand name for naproxen sodium, available in Canada only.

Apo®-Naproxen 
Brand name for naproxen, available in Canada only.

Apo®-Prednisone 
Brand name for prednisone, available in Canada only.

Apo®-Ranitidine 
Brand name for ranitidine HCl, available in Canada only.

A.R.M.: Allergy Relief Medicine
Brand name for tablets containing chlorpheniramine maleate and pseudoephedrine HCl, available OTC in the US.

Astemizole 
H1-blocking non-sedating antihistamine, no longer available in the US. Formerly manufactured by Janssen Pharmaceutica. Used to treat symptoms of chronic idiopathic urticaria and seasonal allergies. Brand Name: Hismanal. For information about the FDA's decision to withdraw astemizole from sale for safety reasons.

AsthmaHaler 
Brand name for epinephrine bitartrate nebulizer inhaler, available OTC in the US.

Atarax 
Brand name for hydroxyzine HCl, available by prescription in US. Also available in Canada.

Atozine 
Brand name for hydroxyzine HCl, available by prescription in the US.

Avomine 
Brand name for promethazine HCl, available by prescription in Australia only.

Azatadine maleate 
H1-blocking antihistamine, related to cyproheptadine, with anti-serotonin, anticholinergic (drying), and sedative effects. Available by prescription in the US and manufactured by Schering-Plough. Prevents, but does not reverse, histamine-mediated responses. Originally approved by the FDA in 1977. Used to treat rhinitis, allergic symptoms, and chronic idiopathic urticaria. Brand Names: Optimine, Trinalin, Zadine.

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B

Banophen 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Banophen Caplets.

Beclodisk 
Brand name for beclomethasone dipropionate. Available in Canada only.

Becloforte Inhaler 
Brand name for beclomethasone dipropionate. Available in Australia only.

Beclomethasone dipropionate 
An anti-inflammatory steroid that decreases inflammation, probably by stabilizing leukocyte lysosomal membranes. Used as an inhalation to treat steroid-dependent asthma and as a nasal spray to treat allergies. Brand names: Aldecin Inhaler, Beclodisk, Becloforte Inhaler, Beclovent, Beconase AQ Nasal Spray, Vancenase AQ Nasal Spray, and Vanceril.

Beclovent 
Brand name for beclomethasone dipropionate. Also available in Canada only as Beclovent Rotacaps.

Beconase AQ Nasal Spray 
Brand name for beclomethasone dipropionate used as a nasal spray that is anti-inflammatory and vasoconstricting. Also available as Beconase Nasal Inhaler. Available by prescription and manufactured in the US by GlaxoSmithKline. Available in the United Kingdom from GlaxoWellcome.

Beldin 
Brand name for diphenhydramine HCl, available OTC in the US.

Belix 
Brand name for diphenhydramine HCl, available OTC in the US.

Bena-D 
Brand name for diphenhydramine HCl, available in the US.

Benadryl® 
Brand name for diphenhydramine HCl, manufactured in the US by Pfizer. Also available in Canada. Also available as Benadryl Allergy, Benadryl 25, and Benadryl Kapseals.

Benahist 
Brand name for diphenhydramine HCl, available in the US.

Ben-Allergin 
Brand name for diphenhydramine HCl, available in the US.

Benoject 
Brand name for diphenhydramine HCl, available in the US.

Bromphen 
Brand name for brompheniramine maleate, available OTC in the US. Liquid form contains alcohol.

Brompheniramine maleate 
H1-blocking antihistamine. Prevents, but does not reverse, histamine-mediated responses. Used to treat rhinitis and allergic symptoms. Brand Names: Bromphen, Chlorphed, Conjec-B, Cophene-B, Dehist, Diamine T.D., Dimetane Extendtabs, Histaject Modified, Nasahist B, ND-Stat Revised B, Oraminic II, and Veltane.

Broniten Mist 
Brand name for epinephrine inhaler and epinephrine bitartrate nebulizer inhaler, available OTC in the US.

Bronkaid Mist Suspension 
Brand name for epinephrine bitartrate nebulizer inhaler, available OTC in the US.

Bronkaid Mistometer 
Brand name for epinephrine inhaler, available OTC in Canada only.

Brufen 
Brand name for ibuprofen. Available in Australia only.

Budesonide 
An anti-inflammatory steroid that decreases inflammation. Used as a nasal spray to treat allergies. Brand name: Rhinocort® Aqua.

Bydramine cough syrup 
Brand of diphenhydramine HCl, available OTC as an oral syrup and manufactured in the US by Major Pharmaceuticals Inc.

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C

Calm X 
Brand name for dimenhydrinate, available OTC in the US.

Celebrex 
Brand name for celecoxib, available by prescription and manufactured in the US by Pfizer. Available in capsules.

Celecoxib 
NSAID that selectively inhibits COX-2, thus producing fewer negative effects than do traditional NSAIDs. Brand name: Celebrex.

Cetirizine hydrochloride 
Non-sedating H1-blocking antihistamine. Brand name: Reactine and Zyrtec.

Children's Dimetapp® ND Non-Drowsy Allergy 
Brand name for loratadine (10 mg), manufactured in the US by Wyeth.

Chlo-Amine 
Brand name for chlorpheniramine maleate, available OTC in the US.

Chlor-100 
Brand name for chlorpheniramine maleate, available OTC in the US.

Chlorate 
Brand name for chlorpheniramine maleate, available OTC in the US.

Chlor-Niramine 
Brand name for chlorpheniramine maleate, available OTC in the US.

Chlorphed 
Brand name for brompheniramine maleate, available OTC in the US.

Chlorpheniramine maleate 
Older sedating H1-blocking antihistamine that can be administered orally or by subcutaneous injection. Prevents, but does not reverse, histamine-mediated responses. Used to treat rhinitis and allergic symptoms. Tablets available OTC. Also called chlorprophenpyridamine maleate. Brand names: Aller-Chlor®, Allergex, Allergy Relief, Chlo-Amine, Chlor-100, Chlorate, Chlor-Niramine, Chlor-Pheniton, Chlor-Pro 10, Chlorspan-12, Chlortab, Chlor-Trimeton®, Chlor-Tripolon, Efidac 24, Genallerate, Novopheniram, Pfeiffer's Allergy, Phenetron, Piriton, Pyranistan, Telachlor, Teldrin®, and Trymegen.

Chlor-Pheniton 
Brand name for chlorpheniramine maleate.

Chlor-Pro 10 
Brand name for chlorpheniramine maleate, available in the US.

Chlorspan-12 
Brand name for chlorpheniramine maleate, available in the US.

Chlortab 
Brand name for chlorpheniramine maleate, available in the US. Also available as Chlortab-4 and Chlortab-8.

Chlor-Trimeton® 
Brand name for chlorpheniramine maleate, available OTC in the US. Also available as Chlor-Trimeton Allergy, Chlor-Trimeton Allergy 12 Hour, and Chlor-Trimeton Repetabs. Liquid form contains alcohol.

Chlor-Tripolon 
Brand name for chlorpheniramine maleate, available only in Canada.

Cimetidine 
H2-blocking antihistamine that prevents the release of acid into the stomach. Used to treat stomach and duodenal ulcers, GERD, and Zollinger-Ellison syndrome. Cimetidine is available as a prescription drug and OTC for the relief of heartburn. Brand name: Tagamet®.

Clarinase 
Brand name for loratadine combined with pseudoephedrine sulphate, available in the United Kingdom. Also available in double-strength tablets as Clarinase 24-hour Relief.

Clarinex® 
Brand name for desloratadine, available by prescription and manufactured in the US by Schering Corp..

Claritin® 
Brand name for loratadine, available OTC and manufactured in the US by Schering-Plough. Also available in Canada. Also available as Claritin Reditabs.

Clemastine fumarate 
H1-blocking antihistamine. Used to treat rhinitis and allergic symptoms. Brand names: Allerhist-1, Contac 12 Hour Allergy, Tavist.

Clorfed
Brand name for extended-release chlorpheniramine maleate and pseudoephedrine HCl tablets, available by prescription in the US. (This is a new brand, introduced in April, 2004.)

Codimal-A 
Brand name for brompheniramine maleate, available in the US.

Compazine® 
Brand name for prochlorperazine maleate, manufactured in the US by GlaxoSmithKline.

Compoz® Nighttime Sleep Aid 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Compoz® Gel Caps.

Comtrex Maximum Strength Caplets
Brand name for tablets containing acetaminophen 500mg (pain reliever/fever reducer), chlorpheniramine maleate, and pseudoephedrine HCl, available OTC in the US.

Conjec-B 
Brand name for brompheniramine maleate, available OTC in the US.

Contac 12 Hour Allergy 
Brand name for clemastine fumarate, available OTC in the US.

Cophene-B 
Brand name for brompheniramine maleate, available in the US.

Corticosteroids
See corticosteroids.

Cromolyn sodium 
Mast cell stabilizer. Cromolyn sodium inhibits the release of mediators from sensitized mast cell. It acts by inhibiting the release of histamine and leukotrienes from the mast cell. It does not have intrinsic vasoconstrictor, antihistamine, or glucocorticoid activity. Brand names: Gastrocrom, Intal, Nalcrom, and Opticrom.

Cyproheptadine hydrochloride 
H1-blocking antihistamine. Used to treat allergic symptoms and pruritus. Brand name: Periactin, PMS-Cyproheptadine.

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D

Dehist 
Brand name for brompheniramine maleate, available in the US.

Deltasone 
Brand name for prednisone, available in the US.

Deptran 
Brand name for doxepin HCl, available in Australia only.

Desloratadine 
Non-sedating H1-blocking antihistamine. Brand name: Clarinex®.

Dexchlor 
Brand name for dexchlorpheniramine maleate, available in the US.

Dexbrompheniraimine maleate 
H1-blocking antihistamine. Brand name: Drixoral Cold & Allergy, Sustained-Action Tablets.

Dexchlorpheniramine maleate 
H1-blocking antihistamine. Prevents, but does not reverse, histamine-mediated responses. Used to treat rhinitis, allergic symptoms, contact dermatitis, and pruritus. Brand names: Dexchlor, Poladex T.D., and Polaramine.

Diamine T.D. 
Brand name for brompheniramine maleate, available in the US.

Dihydrex 
Brand name for diphenhydramine HCl, available as an injection by prescription in the US.

Dilosyn 
Brand name for methdilazine HCl, available by prescription in Australia and Canada only.

Dimenhydrinate 
This H1-blocking antihistamine is a combination of two drugs, diphenhydramine and 8-chlorotheophylline. Dimenhydrinate is used to prevent and treat nausea, vomiting, dizziness, and motion sickness. Approved by the FDA in 1949. Brands: Andrumin, Apo®-Dimenhydrinate, Calm X, Dinate, Dramamine, Dramanate, Dramocen, Dramoject, Dymenate, Gravol, Hydrate, Marmine, Nauseatol, Nico-Vert, Novo-Dimenate, PMS-Dimenhydrinate, Tega-Vert, Travamine, Traveltabs, Travs, Triptone Caplets, Vertab. For more information.

Dimetane Extendtabs 
Brand name for brompheniramine maleate, available OTC in the US. Also available in Canada.

Dimetapp® 12-Hour Non-Drowsy Extentabs®
Brand name for pseudoephedrine HCl (120 mg) — which is not an antihistamine — manufactured in the US by Wyeth.

Dimetapp® Cold & Allergy Tablets
A combination of the sedating H1-blocking antihistamine chlorpheniramine maleate (USP 2 mg), with other ingredients (acetaminophen, USP 325 mg, and phenylephrine HCl, USP 5 mg), manufactured in the US by Wyeth.

Dimetapp® ND Non-Drowsy Allergy, Children's
See Children's Dimetapp® ND Non-Drowsy Allergy.

Dinate 
Brand name for dimenhydrinate, available in the US. A

Diphenacen-50 
Brand name for diphenhydramine HCl, available as an injection by prescription in the US.

Diphenadryl 
Brand name for diphenhydramine HCl, available OTC in the US.

Diphen® Cough 
Brand name for diphenhydramine HCl, available OTC as a syrup in the US.

Diphenhist 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Diphenhist Captabs.

Diphenhydramine hydrochloride (HCl) 
A popular, sedating H1-blocking antihistamine available OTC in pill, capsule, and liquid forms. Prevents, but does not reverse, histamine-mediated responses, particularly histamine's effects on the smooth muscle of the bronchial tubes, GI tract, uterus,, and blood vessels. Also suppresses cough reflex by a direct effect on the medulla (part of the brain). Also available as an injectable drug by prescription. Used to treat rhinitis, allergic symptoms, motion sickness, and Parkinson's Disease. Brand names: Allerdryl, AllerMax Caplets, Aller-med, Allernix, Banophen, Beldin, Belix, Bena-D, Benadryl, Benahist, Ben-Allergin, Benoject, Bydramine cough syrup, Compoz® Nighttime Sleep Aid, Dihydrex, Diphenacen-50, Diphenadryl, Diphen® Cough, Diphenhist, Dormarex 2, Dormin, Durrax, Fynex, Genahist, Gen-D-phen, Hydramine, Hydramyn, Hydril, Hyrexin-50®, Insomnal, Nervine Nighttime Sleep-Aid, Nidryl, Noradryl, Nordryl, Nytol Maximum Strength, Phendry, Siladryl, Sleep-Eze 3, Sominex Formula 2, Tusstat, Twilight Caplets, Unibent Cough, Wehdryl.

Dormarex 2 
Brand name for diphenhydramine HCl, available OTC in the US.

Dormin 
Brand name for diphenhydramine HCl, available OTC in the US.

Doxepin hydrochloride 
A tricyclic antidepressant that has extremely potent antihistamine properties. Brand names: Adapin, Deptran, Novo-Doxepin, Sinequan, and Triadapin.

Dramamine 
Brand name for dimenhydrinate, available OTC in the US. Also available as Children's Dramamine, Dramamine Chewable, and Dramamine Liquid, which may contain alcohol.

Dramanate 
Brand name for dimenhydrinate, available in the US.

Dramocen 
Brand name for dimenhydrinate, available in the US.

Dramoject 
Brand name for dimenhydrinate, available as an injection by prescription in the US.

Drixoral Cold & Allergy, Sustained-Action Tablets
Brand name for tablets containing dexbrompheniraimine maleate (6mg - antihistamine) and pseudoephedrine sulfate (a nasal decongestant), available OTC in the US.

Durrax 
Brand name for hydroxyzine HCl, available by prescription in the US. In France, it may be a brand name for hydroxyzine dichlorhydrate.

Dymenate 
Brand name for dimenhydrinate, available in the US.

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E

Efidac 24 
Brand name for extended-release chlorpheniramine maleate.

Epinephrine (Adrenaline)
A chemical that narrows blood vessels and opens airways in the lungs, which increases blood pressure and decreases wheezing. Brand names: Adrenalin, Broniten Mist, Bronkaid Mistometer, Primatene® Mist, and Sus-Phrine.

Epinephrine bitartrate
A chemical that narrows blood vessels and opens airways in the lungs, which increases blood pressure and decreases wheezing. Epinephrine is injected to halt and reverse anaphylaxis. Brand names: AsthmaHaler, Broniten Mist, Bronkaid Mist Suspension, Medihaler-Epi, and Primatene® Mist Suspension.

Epinephrine hydrochloride
A medication injected to halt and reverse anaphylaxis. Brand names: Adrenalin Chloride, Epi-Pen, and Sus-Phrine.

EpiPen® 
Brand name for an epinephrine auto-injector, which is available by prescription and is used to treat anaphylaxis or severe mast cell attacks. Also available as EpiPen Jr. For more info, see EpiPen.com.

E-Vista
Brand name for hydroxyzine HCl, formerly available by prescription in the US and manufactured by Seatrace Pharmaceuticals, Inc. Important Note: While this medication is no longer available, its name is often confused with that of Evista (raloxifene HCl), which is a selective estrogen receptor modulator, marketed by Eli Lilly for the prevention of osteoporosis in postmenopausal women. For more information.

Excedrin-IB 
Brand name for ibuprofen. Available OTC in the US. Available as caplets or tablets.

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F

Famotidine 
H2-blocking antihistamine that inhibits the action of histamine at receptor sites of the parietal cells, decreasing gastric acid secretion. Brand names: Pepcid and Pepcidine.

Fexofenadine hydrochloride 
A non-sedating H1-blocking antihistamine. Available only by prescription. Brand names: Allegra® and Telfast 120.

Flixotide
Brand name of fluticasone propionate in the form of an inhaler. Manufactured by GlaxoWellcome and available in the United Kingdom. Also available as Flixotide Diskus.

Flonase®
Brand name of fluticasone propionate in the form of a nasal spray. Used to treat nasal allergies. Manufactured in the US by GlaxoSmithKline.

Flovent®
Brand name of fluticasone propionate in the form of an inhaler. Manufactured in the US by GlaxoSmithKline. Available as Flovent Inhalation Aerosol, Flovent Diskus, and Flovent Rotadisk.

Fluticasone propionate 
A synthetic corticosteroid (anti-inflammatory) used to treat allergies (Flonase) and asthma (Flovent). Brand names: Flixotide, Flonase and Flovent.

Fynex 
Brand name for diphenhydramine HCl, available OTC in the US.

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G

Gastrocrom® 
Brand name of cromolyn sodium, manufactured in the US by CellTech Pharmaceuticals and available by prescription.

Genahist 
Brand name for diphenhydramine HCl, available OTC in the US.

Genallerate 
Brand name for chlorpheniramine maleate, available OTCin the US.

Gen-D-phen 
Brand name for diphenhydramine HCl, available OTC in the US.

Genpril 
Brand name for ibuprofen. Available OTC in the US. Available as caplets and tablets.

Gravol 
Brand name for dimenhydrinate, available in Canada only. Also available as Gravol Filmkote, Gravol Filmkote (Junior Strength), Gravol I/M, Gravol I/V, Gravol L/A, and Gravol Liquid.

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H

HCl
Abbreviation for hydrochloride.

Hismanal 
Brand name for astemizole, which is no longer available in the US. For more information, see astemizole.

Histaject Modified 
Brand name for brompheniramine maleate, available in the US.

Histanil 
Brand name for promethazine HCl, available by prescription in Australia only.

Hydramine 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Hydramine Cough.

Hydramyn 
Brand name for diphenhydramine HCl, available OTC in the US.

Hydrate 
Brand name for dimenhydrinate, available in the US.

Hydril 
Brand name for diphenhydramine HCl, available OTC in the US.

Hydroxacen 
Brand name for hydroxyzine HCl, available by prescription in the US.

Hydroxyzine 
Usually refers to hydroxyzine HCl.

Hydroxyzine embonate 
Form of hydroxyzine available only in Australia. Supplied as capsules. Compare to hydroxyzine HCl.

Hydroxyzine hydrochloride 
One of the older, sedating H1-blocking antihistamines, which is especially useful for people who experience intense itchiness. Supplied as tablets, capsules, syrup, and injection. Brand names: ANX®, Anxanil®, Apo®-Hydroxyzine, Atarax, Atozine, Durrax, E-Vista, Hydroxacen, Hyzine-50, Multipax®, Novo-Hydroxyzine®, PMS-Hydroxyzine, Quiess, Restall®, Vistacon-50, Vistacot®, Vistaject, Vistaquel, Vistazine.

Hydroxyzine pamoate 
A sedating H1-blocking antihistamine used to treat anxiety disorders, to relieve itching caused by allergic conditions, and to cause drowsiness. Supplied as capsules and oral suspension. Brand names: Hy-Pam®, Vamate®, Vistaril, and Vistazine.

Hy-Pam® 
Brand name for hydroxyzine pamoate, available in the US..

Hyrexin-50® 
Brand name for diphenhydramine HCl, available as an injection by prescription in the US.

Hyzine-50 
Brand name for hydroxyzine HCl, available by prescription in the US.

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I

Ibuprofen 
NSAID. Brand names: ACT-3, Amersol, Apo®-Ibuprofen, Brufen, Excedrin-IB, Genpril, Medipren, Motrin, Novoprofen, Nuprin, Neurofen, Novoprofen, and Nuprin.

Imodium
Brand name for loperamide. Available OTC in the US.

Insomnal 
Brand name for diphenhydramine HCl available OTC in Canada.

Intal® 
Brand name of cromolyn sodium, in an inhaler. The Intal inhaler is a metered dose aerosol unit for oral inhalation containing micronized cromolyn sodium, used to treat asthma, exercise-induced bronchospasm, and systemic mastocytosis. Also available as a nebulizer solution

Inza-250 
Brand name for naproxen, available in Australia only.

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J

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K

Ketotifen fumarate  
A very potent H1-blocking antihistamine and mast cell stabilizer that is not currently available in the US. Brand names: Zaditen and Zaditor.

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L

Lansoprazole
Proton-pump inhibitor used for short-term treatment of active duodenal ulcer or GERD and for long-term treatment of pathological hypersecretory conditions. Brand name: Prevacid.

Liquid Pred 
Brand name for prednisone, available in the US. Liquid form contains alcohol.

Lomotil
Brand name for a combination of diphenoxylate hydrochloride and atropine sulfate, used to treat acute, nonspecific diarrhea. It is believed to work by increasing smooth muscle tone in the GI tract, inhibiting motility and propulsion, an diminishing secretions. Liquid form contains alcohol.

Loperamide
Used to treat acute, nonspecific diarrhea, acts by inhibiting peristaltic activity and prolonging transit of intestinal contents. Brand name: Imodium.

Loratadine 
Non-sedating H1-blocking antihistamine, which is being touted as the "first non-sedating OTC antihistamine." Its chemical structure prevents entry into the central nervous system. Used to treat symptoms of seasonal allergic rhinitis. Brand names: Alavert, Children's Dimetapp® ND Non-Drowsy Allergy, Clarinase (in combination with pseudoephedrine sulphate), Claritin.

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M

Marmine 
Brand name for dimenhydrinate, available in the US.

Mast cell stabilizer
See mast cell stabilizer.

Medihaler-Epi 
Brand name for epinephrine bitartrate nebulizer inhaler, available OTC in the US.

Medipren 
Brand name for ibuprofen. Available OTC in the US. Available as caplets and tablets.

Methdilazine hydrochloride 
H1-blocking antihistamine, a derivative of phenothiazine. Used as an antipruritic (anti-itch medicine) in dermatoses of various origins, administered in chewable tablets or as oral tablets or a syrup. Prevents, but does not reverse, histamine-mediated responses. Used to treat allergic rhinitis and pruritus. Brand names: Dilosyn, Tacaryl.

Meticorten 
Brand name for prednisone, available in the US.

Montelukast sodium 
Leukotriene inhibitor. Brand name: Singulair.

Motrin 
Brand name for ibuprofen. Available OTC in the US. Available as caplets and tablets.

Multipax® 
Brand name for hydroxyzine HCl in Canada.

Myidyl 
Brand name for triprolidine HCl, available by prescription in the US.

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N

Nalcrom®
Brand name of cromolyn sodium, available by prescription in Canada and New Zealand.

Naprogesic 
Brand name for naproxen sodium, available in Australia only.

Naprosyn 
Brand name for naproxen, available by prescription in the US.

Naprosyn SR 
Brand name for naproxen, available by prescription in Australia and Canada only.

Naproxen 
NSAID. Brand names: Apo®-Naproxen, Inza-250, Naprosyn, Naprosyn SR, Naxen, Novonaprox, and Nu-Naprox.

Naproxen sodium 
NSAID. Brand names: Aleve, Anaprox, Apo®-Napro-Na, Naprogesic, Novonaprox sodium, and Synflex.

Nasacort® Aqua 
Brand of triamcinolone acetonide, available by prescription as a nasal spray and manufactured in the US by Rhône-Poulenc Rorer.

Nasahist B 
Brand name for brompheniramine maleate, available in the US.

Nasalcrom® nasal spray 
Cromolyn sodium, a mast cell stabilizer. OTC medication used to prevent and relieve nasal allergic reactions. Manufactured in the US by Pfizer.

Nauseatol 
Brand name for dimenhydrinate, available in Canada only.

Naxen 
Brand name for naproxen, available by prescription in Australia and Canada only.

ND-Stat Revised B 
Brand name for brompheniramine maleate, available in the US.

Nedocromil 
A mast cell stabilizer used to asthmatic symptoms, including wheezing, shortness of breath, and trouble breathing. It is also used in eye drops to treat allergic reactions in the eyes. Brand name: Alocril.

Nervine Nighttime Sleep-Aid 
Brand name for diphenhydramine HCl, available OTC in the US.

Neurofen 
Brand name for ibuprofen. Available in Australia only.

Nico-Vert 
Brand name for dimenhydrinate, available OTC in the US.

Nidryl 
Brand name for diphenhydramine HCl, available OTC in the US.

Nolahist® 
Brand name for phenindamine, manufactured in the US by Amarin Pharmaceuticals and available OTC.

Nolamine®
Brand name for a product that combines chlorpheniramine maleate, phenindamine, and phenylpropanolamine.

Noradryl 
Brand name for diphenhydramine HCl, available OTC in the US.

Nordryl 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Nordryl Cough, and by prescription as an injection.

Novafed-A Capsules
Brand name for capsules containing chlorpheniramine maleate and pseudoephedrine HCl, available by prescription in the US and manufactured by Marion Merrell Dow.

Novo-Dimenate 
Brand name for dimenhydrinate, available in Canada only.

Novo-Doxepin 
Brand name for doxepin HCl, available in Canada only.

Novo-Hydroxyzine® 
Brand name for hydroxyzine HCl in Canada.

Novonaprox 
Brand name for naproxen, available in Canada only.

Novonaprox sodium 
Brand name for naproxen sodium, available in Canada only.

Novopheniram 
Brand name for chlorpheniramine maleate, available OTCin Australia only. Available in Canada as Novo-Pheniram.

Novo-prednisone 
Brand name for prednisone, available only in Canada.

Novoprofen 
Brand name for ibuprofen, available in Canada only.

NSAIDs
See NSAIDs.

Nu-Naprox 
Brand name for naproxen, available in Canada only.

Nuprin 
Brand name for ibuprofen. Available OTC in the US.

Nytol Maximum Strength 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Nytol with DPH, Nytol QuickCaps, Nytol QuickGels, and Nytol.

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O

Omeprazole
Proton-pump inhibitor used for treatment of GERD and pathological hypersecretory conditions. Brand name: Prilosec.

Omnihist LA Tablets
Brand name for tablets containing chlorpheniramine maleate, phenylephrine, and methscopolamine. Available by prescription in the US and manufactured by We Pharm.

Ondansetron hydrochloride
An antiemetic drug used to treat severe nausea and vomiting. Brand name: Zofran.

Opticrom®
Brand name for cromolyn sodium ophthalmic solution, 4%, which is a clear, colorless, sterile solution intended for topical ophthalmic use. Available by prescription in the US.

Optimine 
Brand name for azatadine maleate, available by prescription in the US as oral tablets, manufactured by Schering-Plough. Optimine syrup was discontinued in the UK in December, 2002.

Oraminic II 
Brand name for brompheniramine maleate, available in the US.

Orasone 
Brand name for prednisone, available in the US.

OTC
Abbreviation for over the counter, a term used to describe medications that are available without a prescription.

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P

Panafcort 
Brand name for prednisone, available only in Australia.

Panasol 
Brand name for prednisone, available in the US.

Panectyl 
Brand name for trimeprazine tartrate, available by prescription in Canada only.

PBZ 
Brand name for Tripelennamine, available by prescription in the US. Liquid form contains tripelennamine citrate, while the tablet-form contains tripelennamine HCl. Liquid form contains alcohol. Also available as PBZ-SR.

Pelamine 
Brand name for tripelennamine HCl, available by prescription in the US.

Pentazine 
Brand name for promethazine HCl, available by prescription in the US.

Pepcid® 
Brand name for famotidine, available by prescription in the US. Available OTC as Pepcid AC in the US.

Pepcidine 
Brand name for famotidine, available by prescription in Australia only.

Pepto Bismol
Brand name for bismuth subsalicylate, used to treat mild, nonspecific diarrhea. Available OTC in the US.

Periactin 
Brand name for cyproheptadine HCl. The oral syrup is available in the US by prescription and manufactured by Merck, but the tablet form was discontinued after 2000.

Pfeiffer's Allergy 
Brand name for chlorpheniramine maleate, available OTC in the US.

Phenameth 
Brand name for promethazine HCl, available by prescription in the US.

Phenazine 
Brand name for promethazine HCl, available by prescription in the US. Available as Phenazine 25 and Phenazine 50.

Phencen-50 
Brand name for promethazine HCl.

Phendry 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Phendryl Children's Allergy Medication.

Phenergan 
Brand name for promethazine HCl, available by prescription in the US. Liquid form contains alcohol. Also available as Phenergan-Fortis and Phenergan-Plain.

Phenetron 
Brand name for chlorpheniramine maleate, available in the US. Liquid form contains alcohol.

Phenindamine 
H1-blocking antihistamine, used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold. Brand name: Nolahist.

Phenoject-50 
Brand name for promethazine HCl, available by prescription in the US.

Piriton 
Brand name for chlorpheniramine maleate, available only in Australia.

PMS-Cyproheptadine 
Brand name for cyproheptadine HCl, available in Canada only.

PMS-Dimenhydrinate 
Brand name for dimenhydrinate, available in Canada only.

PMS-Hydroxyzine 
Brand name for hydroxyzine HCl in Canada.

Poladex T.D. 
Brand name for dexchlorpheniramine maleate, available in the US.

PMS Prochlorperazine®
Brand name for prochlorperazine maleate, available only in Canada.

PMS-Promethazine 
Brand name for promethazine HCl, available by prescription in Canada only.

Polaramine 
Brand name for dexchlorpheniramine maleate, available in the US and Canada. Liquid form contains alcohol. Also available as Polaramine Repetabs.

Prednicen-M 
Brand name for prednisone, available in the US.

Prednisone 
Corticosteroid that decreases inflammation, suppresses the immune response, stimulates bone marrow, and influences protein, fat, and carbohydrate metabolism. Brand names: Apo-Prednisone, Deltasone, Liquid Pred, Meticorten, Novo-prednisone, Orasone, Panafcort, Panasol, Prednicen-M, Prednisone Intensol, Sone, Sterapred, and Winpred.

Prednisone Intensol 
Brand name for prednisone, available in the US. Liquid form contains alcohol.

Prevacid®
Brand name for lansoprazole. Available OTC in the US.

Prilosec®
Brand name for omeprazole. Available OTC in the US.

Primatene® Mist 
Brand name for epinephrine inhaler, manufactured by Wyeth and available OTC in the US.

Primatene® Mist Suspension 
Brand name for epinephrine bitartrate nebulizer inhaler, available OTC in the US.

Primatene® Tablets
Brand name for tablets containing ephedrine HCl USP (12.5 mg), a bronchodilator, and guaifenesin USP (200 mg.), an expectorant, manufactured by Wyeth.

Pro-50 
Brand name for promethazine HCl, available by prescription in the US.

Proazin
Brand name for prochlorperazine maleate, available only in Canada.

Prochlorperazine maleate
Anti-nausea medication. Prochlorperazine maleate is a phenothiazine that blocks dopamine receptors found in an area of the brain involved in the vomiting reflex. Brand names: Compazine®, Proazin, PMS Prochlorperazine®, and Stemetil. For more information.

Prometh 
Brand name for promethazine HCl, available by prescription in the US. Available as Prometh-25 and Prometh-50.

Promethazine hydrochloride 
H1-blocking antihistamine, a derivative of phenothiazine. Prevents, but does not reverse histamine-mediated responses. Used to treat motion sickness, nausea, rhinitis, allergic symptoms, and as a routine preoperative or postoperative sedation or adjunct to analgesics. Brand names: Anergan, Avomine, Histanil, Pentazine, Phenameth, Phenazine, Phencen-50, Phenergan, Phenoject-50, PMS-Promethazine, Pro-50, Prometh, Promethegan, Prorex, Prothazine, and V-Gan.

Promethazine theoclate 
H1-blocking antihistamine, a derivative of phenothiazine. Prevents, but does not reverse histamine-mediated responses. Brand name: Avomine.

Promethegan 
Brand name for promethazine HCl, available by prescription in the US.

Prorex 
Brand name for promethazine HCl, available by prescription in the US. Available as Prorex-25 and Prorex-50.

Prothazine 
Brand name for promethazine HCl, available by prescription in Canada only. Liquid form contains alcohol.

Pseudoephedrine hydrochloride
Decongestant that works by stimulating alpha-receptors in the upper respiratory tract. Can relieve symptoms such as blocked nose, blocked sinuses and catarrh. Pseudoephedrine HCl is not an antihistamine. For more information.

Pyranistan 
Brand name for chlorpheniramine maleate, available OTC in the US.

Pyribenzamine 
Brand name for tripelennamine HCl, available by prescription in the US.

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Q

Quiess 
Brand name for hydroxyzine HCl, available by prescription in the US.

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R

Ranitidine hydrochloride 
H2-blocking antihistamine that inhibits the action of histamine at receptor sites of the parietal cells, decreasing gastric acid secretion. Brand names: Apo-Ranitidine and Zantac.

Reactine 
Brand name for cetirizine HCl, manufactured by Pfizer Canada Inc. and available by prescription in Canada only. Also available as Reactine Extra Strength 24 Hour Relief and Reactine Regular Strength 24 Hour Relief

Restall® 
Brand name for hydroxyzine HCl, and available by prescription in the US.

Rhinocort® Aqua 
Brand of budesonide, available by prescription as a nasal spray and manufactured in the US by Astra Zeneca.

Rofecoxib 
NSAID that selectively inhibits COX-2, thus producing fewer negative effects than do traditional NSAIDs. Brand name: Vioxx.

R-Tannate
Brand name for combination of chlorpheniramine maleate, pyrilamine, and pseudoephedrine HCl Available by prescription in the US as tablets and as a pediatric suspension. Manufactured by Copley Pharmaceutical.

Rynacrom 
Brand name of sodium cromoglicate nasal spray, available by prescription in Canada only.

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S

Seldane 
Brand name for terfenadine, no longer available in the US. Originally available in 1985 as the first prescription antihistamine to relieve the symptoms of allergic rhinitis without causing drowsiness (non-sedating). After its approval, the FDA began receiving reports of fatal and serious instances of cardiac arrhythmia and announced in January 1997 that Seldane would be withdrawn from the market. Was also available in Canada as Seldane Caplets. For info on the class action lawsuit.

Siladryl® 
Brand name for diphenhydramine HCl, available OTC in the US, Inc.

Sinequan 
Brand name for doxepin HCl, available in the US.

Singulair® 
Brand name for montelukast sodium, available by prescription in the US and United Kingdom, and manufactured by Merck.

Sleep-Eze 3 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Sleep-Eze D and Sleep-Eze D Extra Strength.

Sominex 
Brand name for diphenhydramine HCl, available OTC in the US. Also available as Sominex Formula 2.

Sone 
Brand name for prednisone, available only in Australia.

Stemetil
Brand name for prochlorperazine maleate, available in US.

Sterapred 
Brand name for prednisone, available in the US.

Sus-Phrine 
Brand name for epinephrine injection, available in the US.

Synflex 
Brand name for naproxen sodium, available in Canada only.

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T

Tacaryl 
Brand name for methdilazine HCl, available by prescription and formerly manufactured in the US by Westwood Squibb. Discontinued product. Liquid form contains alcohol.

Tagamet® 
Brand name for cimetidine®, manufactured in the US by GlaxoSmithKline. Also available OTC as Tagament HB 200.

Tavist 
Brand name for clemastine fumarate, available OTC in the US and Canada. Also available OTC as Tavist-1 and as Tavist Allergy/Sinus/Headache, which also contains other ingredients.

Tega-Vert 
Brand name for dimenhydrinate, available OTC in the US.

Telachlor 
Brand name for chlorpheniramine maleate, available in the US.

Teldane 
Brand name for terfenadine, available only in Australia.

Teldrin® 
Brand name for a preparation of chlorpheniramine maleate, available OTC in the US. Also available as Teldrin HBP.

Telfast 120® 
Brand name for fexofenadine HCl. Manufactured in the US and distributed in the United Kingdom by Hoechst Marion Roussel. Also available as Telfast D.

Temaril 
Brand name for trimeprazine tartrate, available by prescription in the US. Liquid form contains alcohol.

Terfenadine 
First non-sedating H1 antihistamine available by prescription in the US. No longer available in the US. Used to treat rhinitis and allergic symptoms. See Seldane for further information. Brand name: Seldane, Teldane.

Travamine 
Brand name for dimenhydrinate, available in Canada only.

Traveltabs 
Brand name for dimenhydrinate, available in Canada only.

Travs 
Brand name for dimenhydrinate, available in Australia only.

Triadapin 
Brand name for doxepin HCl, available in Canada only.

Triamcinolone acetonide 
An anti-inflammatory steroid used to treat nasal allergic symptoms. Brand name: Nasacort® Aqua.

Triaminacin Cold, Allergy, Sinus Medicine Tablets
Brand name for tablets containing acetaminophen 650mg (pain reliever/fever reducer), chlorpheniramine maleate, and pseudoephedrine HCl, available OTC in the US.

Tri-Gestan S Susp
Brand name for capsules containing chlorpheniramine maleate, pyrilamine, and pseudoephedrine HCl, available by prescription in the US and manufactured by Mova.

Trimeprazine tartrate 
H1-blocking antihistamine, a derivative of phenothiazine. Prevents, but does not reverse histamine-mediated responses. Used to treat pruritus. Brand names: Panectyl, Temaril, and Vallergan.

Trinalin
Brand name for tablets containing azatadine maleate and pseudoephedrine sulfate (a decongestant), available in the US.

Tripelennamine citrate 
H1-blocking antihistamine. Prevents, but does not reverse histamine-mediated responses. Brand name: PBZ.

Tripelennamine hydrochloride 
H1-blocking antihistamine. Prevents, but does not reverse histamine-mediated responses. Used to treat rhinitis and allergic symptoms. Brand names: PBZ, Pelamine, and Pyribenzamine.

Triprolidine hydrochloride 
H1-blocking antihistamine. Prevents, but does not reverse histamine-mediated responses. Used to treat colds and allergic symptoms. Brand names: Alleract and Myidyl.

Triptone Caplets 
Brand name for dimenhydrinate, available OTC in the US.

Trymegen 
Brand name for a preparation of chlorpheniramine maleate, available OTC in the US.

Tusstat 
Brand name for diphenhydramine HCl, available OTC in the US.

Twilight Caplets 
Brand name for diphenhydramine HCl, available OTC in the US.

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U

Unibent Cough 
Brand name for diphenhydramine HCl, available OTC in the US.

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V

Vallergan 
Brand name for trimeprazine tartrate, available by prescription in Australia only.

Vamate® 
Brand name for Hydroxyzine pamoate.

Vancenase AQ Nasal Spray 
Brand name for beclomethasone dipropionate used as a nasal spray that is anti-inflammatory and vasoconstricting. Also available as Vancenase Nasal Inhaler. Available by prescription and manufactured in the US by Schering Laboratories.

Vanceril 
Brand name for beclomethasone dipropionate, used as an inhalation to treat asthma. Available by prescription and manufactured in the US by Schering Laboratories.

Veltane 
Brand name for brompheniramine maleate, available in the US.

Vertab 
Brand name for dimenhydrinate, available in the US.

V-Gan 
Brand name for promethazine HCl, available by prescription in the US. Available as V-Gan-25 and V-Gan-50.

Vioxx 
Brand naem for rofecoxib, available by prescription and manufactured in the US by Merck. Available in tablets and as an oral suspension.

Vistacon-50 
Brand name for hydroxyzine HCl, available by prescription in the US.

Vistacot® 
Brand name for hydroxyzine HCl, available by prescription in the US.

Vistaject 
Brand name for hydroxyzine HCl, available by prescription in the US.

Vistaquel 
Brand name for hydroxyzine HCl, available by prescription in the US.

Vistaril® 
Brand name for Hydroxyzine pamoate, manufactured in the US by Pfizer.

Vistazine 
Brand name for Hydroxyzine pamoate, manufactured in the US by Pfizer.

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W

Wehdryl 
Brand name for diphenhydramine HCl, available in the US.

Winpred 
Brand name for prednisone, available only in Canada.

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X

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Y

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Z

Zadine 
Brand name for azatadine maleate, available by prescription in Australia only.

Zaditen® 
Brand name for ketotifen fumarate, used as an anti-allergy eye drop that combines the actions of an antihistamine and a mast cell stabilizer with a distinct inhibitory effect on eosinophil infiltration, activation, and degranulation. Available by prescription and manufactured in the US by Novartis.

Zaditor® 
Brand name for ketotifen fumarate ophthalmic solution, used for the prevention of ocular itching due to allergic conjunctivitis. Available by prescription in the US and manufactured by Novartis Ophthalmics.

Zafirlukast 
A synthetic, selective leukotriene receptor antagonist that is most often prescribed to prevent and treat asthma in adults and children 5 years of age and older. Available only by prescription. Not for use in reversal of acute asthma attacks. Brand name: Accolate®.

Zantac® 
Brand name for ranitidine HCl, available OTC in the US.

Zileuton 
An orally active inhibitor of the enzyme that catalyzes the formation of leukotrienes from arachidonic acid. Brand name: Zyflo™ Filmtab®.

Zofran®
Brand name for ondansetron HCl, an antiemetic available by prescription and manufactured in the US by GlaxoSmithKline.

Zyflo™ Filmtab® 
Brand name for zileuton, available by prescription and manufactured in the US by Abbott Laboratories.

Zyrtec® 
Brand of cetirizine HCl, available by prescription and manufactured in the US by Pfizer. Zyrtec has been available in the US since 1996 and outside the United States since 1987. Also available in Canada.

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Are there other medications used to treat the symptoms of mast cell-related diseases that are not listed? Please send your suggestions to: Candace Van Auken.


Our thanks go to Stan Boney for sharing his spreadsheet of masto meds — it was a big help in creating this page!

A variety of Internet sources have been used in developing this page. Also used was the Nursing 96 Drug Handbook (Springhouse, PA: Sprinhouse Corporation Nursing96 Books, © 1996, ISBN: 0-87434-817-X).


This page was last updated on June 9, 2004.

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