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Deciphering the Role of Frataxin

4. References

  1. Durr, A. Cossee, M., Agid, Y. Campuzano, V., Mignard, C., Penet, C., Mandel, J.L., Brice, A., and Koenig, M. Clinical and genetic abnormalities in patients with Friedreich's ataxia. New England Journal of Medicine 335, 1169-1175 (1996).

  2. Finocchiaro, G. Baio, G., Micossi, P., Pozza, G., and Di Donato, S. Glucose metabolism alterations in Friedreich's ataxia. Neurology 38, 1292-1296 (1988).

  3. Wood, N. Diagnosing Friedreich's ataxia. Archives of Disease in Childhood 78, 204-207 (1998).

  4. Campuzano, V., Montermini, L., Molto, M.D., Pianese, L., Cossee, M., Cavalcanti, F., Monros, E., Rodius, F., Duclos, F., Monticelli, A., Zara, F., Canizares, J., Koutnikova, H., Bidichandani, S.I., Gellera, C., Brice, A., Trouillas, P., De Michele, G., Filla, A., De Frutos, R., Palau, F., Patel, P.I., Di Donato, S., Mandel, J-L., Cocozza, S., Koenig, M., and Pandolfo, M. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA repeat expansion. Science 271, 1423-1427 (1996).

  5. Koutnikova, H., Campuzano, V., Foury, F., Dolle, P., Cazzalini, O., and Koenig, M. Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin. Nature Genetics 16, 345-351 (1997).

  6. Koenig, M., and Mandel, J-L. Deciphering the cause of Friedreich ataxia. Current Opinion in Neurobiology 7, 689-694 (1997).

  7. Campuzano, V., Montermini, L., Lutz, Y., Cova, L., Hindelang, C., Jiralerspong, S., Trottier, Y., Kish, S., Faucheux, B., Trouillas, P., Authier, F., Durr, A., Mandel, J-L., Vescovi, A., Pandolfo, M., and Koenig, M. Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes. Human Molecular Genetics 6, 1771-1780 (1997).

  8. Babcock, M., de Silva, D., Oaks, R., Davis-Kaplan, S., Jiralerspong, S., Montermini, L., Pandolfo, M., and Kaplan, J. Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science 276, 1709-1712 (1997).

  9. Rotig, A., de Lonlay, P., Chretien, D., Foury, F., Koenig, M., Sidi, D., Munnich, A., and Rustin, P. Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia. Nature Genetics 17, 215-217 (1997).

  10. Fridovitch, I. Superoxide radical and superoxide dismutases. Annual Reviews of Biochemistry 64, 97-112 (1995).

  11. Wong, A., Taron, F., Gellera, C., and Cortopassi. The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress. Abstract 2286. The American Society of Human Genetics 48th Annual Meeting (1998).

  12. Wilson, R. and Roof, D. Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homolog. Nature Genetics 16, 352-357 (1997).

  13. Knight, S.A.B, Sepuri, N.B.V., Pain, D., and Dancis, A. Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondria iron homeostasis. Journal of Biological Chemistry 273, 18389-18393 (1998).

  14. Li, L. and Kaplan, J. Characterization of two homologous yeast genes that encode mitochondrial iron transporters. Journal of Biological Chemistry 272, 28485-28493 (1997).

  15. Iancu, T.C.; Deugnier, Y.; Halliday, J.W.; Powell, L.W.; and Brissot, P. Ultrastructural sequences during liver iron overload in genetic hemochromatosis. Journal of Hepatology 4, 628-38 (1997).

  16. Wilson, R., Lynch, D., and Fischbeck, K. Normal serum iron and ferritin concentrations in patients with Friedreich's ataxia. Annals of Neurology 44, 132-134 (1998).

  17. Agatep, R., Kirkpatrick, R.D., Parchaliuk, D.L., Woods, R.A., and Gietz, R.D. Transformation of Saccharomyces cerevisiae by the lithium acetate/single-stranded carrier DNA/polyethylene glycol protocol. Technical Tips Online, Article # 01525 (1998).

  18. Daum, G., Bohni, P., and Schatz, G. Import of proteins into the mitochondria. Journal of Biological Chemistry 257, 13028-13033 (1982).

  19. Kuster, B., and Mann, M. Identifying proteins and post-translational modifications by mass spectrometry. Current Opinion in Structural Biology 8, 393-400 (1998).

  20. Finley, R.L. and Brent, R. Interaction trap cloning with yeast. Gene Probes - A Practical Approach. Oxford University Press, http://www.molsci.org/brentlabweb/brent/interaction_trap/methods_paper.txt (draft).

  21. Brachmann, R.K., and Boeke, J. Tag games in yeast: the two-hybrid system and beyond. Current Opinion in Biotechnology 8, 561-568 (1997).

  22. Origene catalog, http://www.origene.com/yeast.htm (1998).

  23. Yaffe, M. Guide to Yeast Genetics and Molecular Biology (Guthrie, C. and Fink, G.R. eds.), Academic Press, New York, pp. 627-643 (1991).

  24. Sherman, F. Guide to Yeast Genetics and Molecular Biology (Guthrie, C. and Fink, G.R. eds.), Academic Press, New York, pp. 3-21 (1991).

  25. Sherman, F. and Hicks, J. Guide to Yeast Genetics and Molecular Biology (Guthrie, C. and Fink, G.R. eds.), Academic Press, New York, pp. 21-37 (1991).

  26. Foury, F. and Cazzalini, O. Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in the mitochondria. FEBS Letters 411, 373-377 (1997).




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